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RSV and Synagis

What is RSV?

Respiratory syncytial virus (RSV) is a virus that causes a lung infection called bronchiolitis. Babies commonly get RSV. Two out of three infants are infected with RSV during their first year of life. RSV is highly contagious. It is spread by contact with infected fluids from the nose or mouth and through droplets in the air from coughing. RSV usually occurs in the wintertime.

Some children with RSV may have pneumonia or they need oxygen. Children born prematurely or who get RSV during the first months of life are more likely to have these complications.

Toddlers and older children with RSV usually do not have serious problems. For these children, RSV is usually no worse than a bad cold.

A vaccine is not available for RSV.

What is Synagis?

Synagis is a medicine that helps prevent serious lung infections caused by RSV. Synagis is an antibody that is made using DNA technology. Full-term babies get virus-fighting substances called antibodies from their mothers during pregnancy. These antibodies help to fight RSV and other viruses. But babies born prematurely often do not get enough of these antibodies before birth.

This medicine is not a treatment for children who already have RSV.

Should my child get Synagis?

This medicine is given only to children under 2 years old at high risk for serious complications if they should get RSV. These children include:

  • some premature infants who were born at least 5 weeks early
  • children with bronchopulmonary dysplasia (BPD), a lung disease that causes babies to need extra oxygen because the lungs do not work properly
  • children with other conditions that put them in a high-risk group.

Synagis should not be given to children who have previously had a severe allergic reaction to Synagis. Check with your health care provider if you have questions about whether your child should receive Synagis.

How is Synagis given?

Synagis is given by injection into the leg muscle. Your child should get the Synagis shot every month throughout the winter and early spring. Synagis may be given with other routine immunizations.

What are the side effects of Synagis?

The place where the shot was given may become red or tender. Your child has a slight risk of vomiting or having diarrhea. Rarely, children develop cold symptoms, an ear infection, rash, pain, or sore throat. As with any medicine, there is a risk that it could cause an allergic reaction.

How can I learn more?

Ask your health care provider about Synagis. He or she can give you the package insert or suggest other sources of information.

Written by Robert Brayden, MD, Associate Professor of Pediatrics, University of Colorado School of Medicine.
Published by McKesson Provider Technologies.
Last modified: 2006-09-12
Last reviewed: 2006-08-22
This content is reviewed periodically and is subject to change as new health information becomes available. The information is intended to inform and educate and is not a replacement for medical evaluation, advice, diagnosis or treatment by a healthcare professional.
Copyright 2006 McKesson Corporation and/or one of its subsidiaries. All Rights Reserved.
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